Cargando…
Coronaviruses Nsp5 Antagonizes Porcine Gasdermin D-Mediated Pyroptosis by Cleaving Pore-Forming p30 Fragment
Coronaviruses (CoVs) are a family of RNA viruses that typically cause respiratory, enteric, and hepatic diseases in animals and humans. Here, we use porcine epidemic diarrhea virus (PEDV) as a model of CoVs to illustrate the reciprocal regulation between CoV infection and pyroptosis. For the first t...
Autores principales: | Shi, Fushan, Lv, Qian, Wang, Tingjun, Xu, Jidong, Xu, Wei, Shi, Yuhua, Fu, Xinyu, Yang, Tianming, Yang, Yang, Zhuang, Lenan, Fang, Weihuan, Gu, Jinyan, Li, Xiaoliang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749417/ https://www.ncbi.nlm.nih.gov/pubmed/35012343 http://dx.doi.org/10.1128/mbio.02739-21 |
Ejemplares similares
-
Broad antagonism of coronaviruses nsp5 to evade the host antiviral responses by cleaving POLDIP3
por: Wu, Yang, et al.
Publicado: (2023) -
Arterivirus nsp4 Antagonizes Interferon Beta Production by Proteolytically Cleaving NEMO at Multiple Sites
por: Chen, Jiyao, et al.
Publicado: (2019) -
Pyroptosis inhibiting nanobodies block Gasdermin D pore formation
por: Kopp, Anja, et al.
Publicado: (2023) -
FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation
por: Hu, Jun Jacob, et al.
Publicado: (2020) -
Gasdermin D in pyroptosis
por: Burdette, Brandon E., et al.
Publicado: (2021)