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Intranuclear Positions of HIV-1 Proviruses Are Dynamic and Do Not Correlate with Transcriptional Activity

The relationship between spatiotemporal distribution of HIV-1 proviruses and their transcriptional activity is not well understood. To elucidate the intranuclear positions of transcriptionally active HIV-1 proviruses, we utilized an RNA fluorescence in situ hybridization assay and RNA stem loops tha...

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Detalles Bibliográficos
Autores principales: Burdick, Ryan C., Deleage, Claire, Duchon, Alice, Estes, Jacob D., Hu, Wei-Shau, Pathak, Vinay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749423/
https://www.ncbi.nlm.nih.gov/pubmed/35012348
http://dx.doi.org/10.1128/mbio.03256-21