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Conformation of HIV-1 Envelope Governs Rhesus CD4 Usage and Simian-Human Immunodeficiency Virus Replication

Infection of rhesus macaques with simian-human immunodeficiency viruses (SHIVs) is the preferred model system for vaccine development because SHIVs encode human immunodeficiency virus type 1 (HIV-1) envelope glycoproteins (Envs)—a key target of HIV-1 neutralizing antibodies. Since the goal of vaccin...

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Detalles Bibliográficos
Autores principales:	Vilmen, Geraldine, Smith, Anna C., Benet, Hector Cervera, Shukla, Rajni Kant, Larue, Ross C., Herschhorn, Alon, Sharma, Amit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749432/ https://www.ncbi.nlm.nih.gov/pubmed/35012342 http://dx.doi.org/10.1128/mbio.02752-21

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