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Protective antigenic sites identified in respiratory syncytial virus fusion protein reveals importance of p27 domain

Respiratory syncytial virus (RSV) vaccines primarily focused on surface fusion (F) protein are under development. Therefore, to identify RSV‐F protective epitopes, we evaluated 14 antigenic sites recognized following primary human RSV infection. BALB/c mice were vaccinated with F peptides, F protein...

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Detalles Bibliográficos
Autores principales: Lee, Jeehyun, Lee, Youri, Klenow, Laura, Coyle, Elizabeth M, Tang, Juanjie, Ravichandran, Supriya, Golding, Hana, Khurana, Surender
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749483/
https://www.ncbi.nlm.nih.gov/pubmed/34750984
http://dx.doi.org/10.15252/emmm.202013847