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The association between therapeutic plasma exchange and the risk of mortality among patients critically ill with COVID-19: a meta-analysis
Background: Cytokine storm has been widely known to contribute to the development of the critical condition in patients with coronavirus disease 2019 (COVID-19), and studies had been conducted to assess the potential aspect of cytokine storm elimination by performing therapeutic plasma exchange (TPE...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
F1000 Research Limited
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749910/ https://www.ncbi.nlm.nih.gov/pubmed/35083038 http://dx.doi.org/10.12688/f1000research.74972.1 |
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| author | Wardhani, Shinta Oktya Fajar, Jonny Karunia Soegiarto, Gatot Wulandari, Laksmi Maliga, Helnida Anggun Ilmawan, Muhammad Merysa, Risna Simamora, Arlentina Bentivolia Aini, Qurrata Noviantari, Komang Lestari, Ayu Widya Harnila, Maria Yoheni Syafi'i, Imam Djianzonie, Jane Andrea Christiano Siagian, Nenci Nining, Sri Hanim, Risyda Zakiyah Wahyuni, Wahyuni Aulia, Fitri Juliansyah, Juliansyah Mahmud, Reflin Tamara, Fredo Mahendra, Aditya Indra Wowor, Amanda Cininta Baladraf, Fikri Hadinata, Ponda Hernest Ikkeputri, Adhityari Nadya, Hana Kartini, Dessy Aprilia Husnah, Milda Nainu, Firzan Harapan, Harapan |
| author_facet | Wardhani, Shinta Oktya Fajar, Jonny Karunia Soegiarto, Gatot Wulandari, Laksmi Maliga, Helnida Anggun Ilmawan, Muhammad Merysa, Risna Simamora, Arlentina Bentivolia Aini, Qurrata Noviantari, Komang Lestari, Ayu Widya Harnila, Maria Yoheni Syafi'i, Imam Djianzonie, Jane Andrea Christiano Siagian, Nenci Nining, Sri Hanim, Risyda Zakiyah Wahyuni, Wahyuni Aulia, Fitri Juliansyah, Juliansyah Mahmud, Reflin Tamara, Fredo Mahendra, Aditya Indra Wowor, Amanda Cininta Baladraf, Fikri Hadinata, Ponda Hernest Ikkeputri, Adhityari Nadya, Hana Kartini, Dessy Aprilia Husnah, Milda Nainu, Firzan Harapan, Harapan |
| author_sort | Wardhani, Shinta Oktya |
| collection | PubMed |
| description | Background: Cytokine storm has been widely known to contribute to the development of the critical condition in patients with coronavirus disease 2019 (COVID-19), and studies had been conducted to assess the potential aspect of cytokine storm elimination by performing therapeutic plasma exchange (TPE). However, contradictory findings were observed. The objective of this study was to assess the association between TPE and the reduction of mortality of critically ill COVID-19 patients. Methods: A meta-analysis was conducted by collecting data from PubMed, Scopus, and Web of Science. Data on the mortality rate of critically ill COVID-19 patients treated with TPE plus standard of care and that of patients treated with standard of care alone were analyzed using a Z test. Results: We included a total of four papers assessing the association between TPE and the risk of mortality among critically ill COVID-19 patients. Our findings suggested that critically ill COVID-19 patients treated with TPE had lower risk of mortality compared to those without TPE treatment. Conclusion: Our study has identified the potential benefits of TPE in reducing the risk of mortality among critically ill COVID-19 patients. |
| format | Online Article Text |
| id | pubmed-8749910 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | F1000 Research Limited |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-87499102022-01-25 The association between therapeutic plasma exchange and the risk of mortality among patients critically ill with COVID-19: a meta-analysis Wardhani, Shinta Oktya Fajar, Jonny Karunia Soegiarto, Gatot Wulandari, Laksmi Maliga, Helnida Anggun Ilmawan, Muhammad Merysa, Risna Simamora, Arlentina Bentivolia Aini, Qurrata Noviantari, Komang Lestari, Ayu Widya Harnila, Maria Yoheni Syafi'i, Imam Djianzonie, Jane Andrea Christiano Siagian, Nenci Nining, Sri Hanim, Risyda Zakiyah Wahyuni, Wahyuni Aulia, Fitri Juliansyah, Juliansyah Mahmud, Reflin Tamara, Fredo Mahendra, Aditya Indra Wowor, Amanda Cininta Baladraf, Fikri Hadinata, Ponda Hernest Ikkeputri, Adhityari Nadya, Hana Kartini, Dessy Aprilia Husnah, Milda Nainu, Firzan Harapan, Harapan F1000Res Systematic Review Background: Cytokine storm has been widely known to contribute to the development of the critical condition in patients with coronavirus disease 2019 (COVID-19), and studies had been conducted to assess the potential aspect of cytokine storm elimination by performing therapeutic plasma exchange (TPE). However, contradictory findings were observed. The objective of this study was to assess the association between TPE and the reduction of mortality of critically ill COVID-19 patients. Methods: A meta-analysis was conducted by collecting data from PubMed, Scopus, and Web of Science. Data on the mortality rate of critically ill COVID-19 patients treated with TPE plus standard of care and that of patients treated with standard of care alone were analyzed using a Z test. Results: We included a total of four papers assessing the association between TPE and the risk of mortality among critically ill COVID-19 patients. Our findings suggested that critically ill COVID-19 patients treated with TPE had lower risk of mortality compared to those without TPE treatment. Conclusion: Our study has identified the potential benefits of TPE in reducing the risk of mortality among critically ill COVID-19 patients. F1000 Research Limited 2021-12-14 /pmc/articles/PMC8749910/ /pubmed/35083038 http://dx.doi.org/10.12688/f1000research.74972.1 Text en Copyright: © 2021 Wardhani SO et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Systematic Review Wardhani, Shinta Oktya Fajar, Jonny Karunia Soegiarto, Gatot Wulandari, Laksmi Maliga, Helnida Anggun Ilmawan, Muhammad Merysa, Risna Simamora, Arlentina Bentivolia Aini, Qurrata Noviantari, Komang Lestari, Ayu Widya Harnila, Maria Yoheni Syafi'i, Imam Djianzonie, Jane Andrea Christiano Siagian, Nenci Nining, Sri Hanim, Risyda Zakiyah Wahyuni, Wahyuni Aulia, Fitri Juliansyah, Juliansyah Mahmud, Reflin Tamara, Fredo Mahendra, Aditya Indra Wowor, Amanda Cininta Baladraf, Fikri Hadinata, Ponda Hernest Ikkeputri, Adhityari Nadya, Hana Kartini, Dessy Aprilia Husnah, Milda Nainu, Firzan Harapan, Harapan The association between therapeutic plasma exchange and the risk of mortality among patients critically ill with COVID-19: a meta-analysis |
| title | The association between therapeutic plasma exchange and the risk of mortality among patients critically ill with COVID-19: a meta-analysis |
| title_full | The association between therapeutic plasma exchange and the risk of mortality among patients critically ill with COVID-19: a meta-analysis |
| title_fullStr | The association between therapeutic plasma exchange and the risk of mortality among patients critically ill with COVID-19: a meta-analysis |
| title_full_unstemmed | The association between therapeutic plasma exchange and the risk of mortality among patients critically ill with COVID-19: a meta-analysis |
| title_short | The association between therapeutic plasma exchange and the risk of mortality among patients critically ill with COVID-19: a meta-analysis |
| title_sort | association between therapeutic plasma exchange and the risk of mortality among patients critically ill with covid-19: a meta-analysis |
| topic | Systematic Review |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749910/ https://www.ncbi.nlm.nih.gov/pubmed/35083038 http://dx.doi.org/10.12688/f1000research.74972.1 |
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