Cargando…

Actionable Molecular Alterations Are Revealed in Majority of Advanced Non-Small Cell Lung Cancer Patients by Genomic Tumor Profiling at Progression after First Line Treatment

SIMPLE SUMMARY: In precision medicine, cancer patients are treated with drugs that target specific molecular alterations found in their cancer cells. As new drugs for specific targets emerge, possibilities expand. Our prospective clinical study explored the possibilities of receiving targeted treatm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Frank, Malene Støchkel, Bodtger, Uffe, Gehl, Julie, Ahlborn, Lise Barlebo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749927/ https://www.ncbi.nlm.nih.gov/pubmed/35008297 http://dx.doi.org/10.3390/cancers14010132

Ejemplares similares

Circulating Tumor DNA Monitoring Reveals Molecular Progression before Radiologic Progression in a Real-life Cohort of Patients with Advanced Non–small Cell Lung Cancer
por: Frank, Malene S., et al.
Publicado: (2022)

Detection of copy number alterations in cell-free tumor DNA from plasma
por: Østrup, Olga, et al.
Publicado: (2017)

Fractionated palliative thoracic radiotherapy in non-small cell lung cancer – futile or worth-while?
por: Støchkel Frank, Malene, et al.
Publicado: (2018)

Detection of circulating tumor-derived material in peripheral blood of pediatric sarcoma patients: A systematic review
por: Kjær, Eva Kristine Ruud, et al.
Publicado: (2023)

The impact of a personalised action plan delivered at discharge to patients with COPD on readmissions: a pilot study
por: Hegelund, Annette, et al.
Publicado: (2019)

Coherence between self-reported and objectively measured physical activity in patients with chronic obstructive lung disease: a systematic review
por: Thyregod, Mimi, et al.
Publicado: (2016)

Maternal versus paternal inheritance of a 132 bp 11p15.5 microdeletion affecting KCNQ1OT1 and associated phenotypes
por: Stoltze, Ulrik Kristoffer, et al.
Publicado: (2023)

ProTarget: a Danish Nationwide Clinical Trial on Targeted Cancer Treatment based on genomic profiling – a national, phase 2, prospective, multi-drug, non-randomized, open-label basket trial
por: Kringelbach, Tina, et al.
Publicado: (2023)

The experience of being a participant in one’s own care at discharge and at home, following a severe acute exacerbation in chronic obstructive pulmonary disease: a longitudinal study
por: Andersen, Ingrid Charlotte, et al.
Publicado: (2017)

Plasma total cell-free DNA is a prognostic biomarker of overall survival in metastatic solid tumour patients
por: Viller Tuxen, Ida, et al.
Publicado: (2019)

Lemierre’s syndrome: current perspectives on diagnosis and management
por: Johannesen, Katrine M, et al.
Publicado: (2016)

The impact of pulmonary rehabilitation on severe physical inactivity in patients with chronic obstructive pulmonary disease: a pilot study
por: Thyregod, Mimi, et al.
Publicado: (2018)

Zoological physics: quantitative models of body design, actions, and physical limitations of animals
por: Ahlborn, Boye K
Publicado: (2004)

Using structured progress to measure competence in flexible bronchoscopy
por: Cold, Kristoffer Mazanti, et al.
Publicado: (2020)

Shaping Better Rehabilitation to Chronic Obstructive Pulmonary Disease Patients: Experiences of Nurses and Colleagues With an Interdisciplinary Telerehabilitation Intervention
por: Simonÿ, Charlotte, et al.
Publicado: (2022)

Accuracy and consequences of same-day, invasive lung cancer workup – a retrospective study in patients treated with surgical resection
por: Madsen, Kirsten Riis, et al.
Publicado: (2016)

Bad news itself or just the messenger? The high mortality of Fusobacterium spp. infections is related to disseminated malignancy and other comorbidities
por: Johannesen, Katrine, et al.
Publicado: (2016)

Primary pulmonary adenocarcinoma in a 16-year-old boy – a five-year follow-up
por: Måreng, Ane Stillits, et al.
Publicado: (2016)

Striving for Confidence and Satisfaction in Everyday Life with Chronic Obstructive Pulmonary Disease: Rationale and Content of the Tele-Rehabilitation Programme >C☺PD-Life>>
por: Simonÿ, Charlotte, et al.
Publicado: (2019)

Circulating tumor DNA as a marker of treatment response in BRAF V600E mutated non-melanoma solid tumors
por: Ahlborn, Lise Barlebo, et al.
Publicado: (2018)

Cell-free DNA in newly diagnosed patients with glioblastoma – a clinical prospective feasibility study
por: Nørøxe, Dorte Schou, et al.
Publicado: (2019)

Disseminated lung cancer presenting as a rectal mass
por: Noergaard, Mia M., et al.
Publicado: (2016)

Breathing through a troubled life – a phenomenological-hermeneutic study of chronic obstructive pulmonary disease patients’ lived experiences during the course of pulmonary rehabilitation
por: Simonÿ, Charlotte, et al.
Publicado: (2019)

Upper airway symptoms associate with the eosinophilic phenotype of COPD
por: Obling, Nicolai, et al.
Publicado: (2021)

Changes in systemic inflammation after pulmonary rehabilitation in patients with COPD and severe physical inactivity – an exploratory study
por: Thyregod, Mimi, et al.
Publicado: (2022)

Investigation of the mechanisms of action behind Electromotive Drug Administration (EMDA)
por: Kos, Bor, et al.
Publicado: (2016)

Difference in Membrane Repair Capacity Between Cancer Cell Lines and a Normal Cell Line
por: Frandsen, Stine Krog, et al.
Publicado: (2016)

The value of computed tomography in discriminating malignant from non-malignant causes of unresolved unilateral pleural effusions: a systematic review
por: Reuter, Simon, et al.
Publicado: (2019)

A rare clinical presentation of Waldenström Macroglobulinemia mimicking lung cancer
por: Laursen, Michael RT., et al.
Publicado: (2022)

Lung function in Lolland‐Falster Health Study (LOFUS)
por: Jacobsen, Katja Kemp, et al.
Publicado: (2022)

Suspected Lung Cancer with Suspicious Liver Lesions: Diagnostic Yield and Safety of Same-Day Bronchoscopy and Liver Biopsy in the Hands of a Pulmonologist
por: Ahmadzai, Sina, et al.
Publicado: (2023)

Real-World Outcomes of Immunotherapy in Second- or Later-Line Non-Small Cell Lung Cancer with Actionable Genetic Alterations
por: Jun, Soojin, et al.
Publicado: (2023)

Putting the pieces together: A qualitative study exploring perspectives on self-management and exercise behavior among people living with multimorbidity, healthcare professionals, relatives, and patient advocates
por: Jäger, Madalina, et al.
Publicado: (2022)

Immune checkpoint inhibitors beyond first-line progression with prior immunotherapy in patients with advanced non-small cell lung cancer
por: Xu, Manyi, et al.
Publicado: (2023)

Diagnostic work-up in patients with possible asthma referred to a university hospital
por: Backer, Vibeke, et al.
Publicado: (2015)

The Danish National Database for Asthma
por: Backer, Vibeke, et al.
Publicado: (2016)

Endoscopic ultrasound-guided ascites aspiration in the hands of the chest physician using the EBUS endoscope in the oesophagus
por: Nessar, Rafi, et al.
Publicado: (2020)

Physiological changes related to 10 weeks of singing for lung health in patients with COPD
por: Kaasgaard, Mette, et al.
Publicado: (2022)

Calcium Electroporation: Evidence for Differential Effects in Normal and Malignant Cell Lines, Evaluated in a 3D Spheroid Model
por: Frandsen, Stine Krog, et al.
Publicado: (2015)

Asymptomatic silicone induced granulomatous disease diagnosed by endobronchial ultrasound with real-time guided transbronchial needle aspiration (EBUS-TBNA)
por: Naur, Therese Maria Henriette, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_g7n8igqsqpiuop428pr4i89gpe