Cargando…

3D Cell Culture Models as Recapitulators of the Tumor Microenvironment for the Screening of Anti-Cancer Drugs

SIMPLE SUMMARY: Three-dimensional (3D) cell culture models have been proposed as alternatives for initial drug screening to increase drug development efficiency. In addition to their ability to reproduce key aspects of the tumor architecture and microenvironment, 3D cell culture models may help decr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Barbosa, Mélanie A. G., Xavier, Cristina P. R., Pereira, Rúben F., Petrikaitė, Vilma, Vasconcelos, M. Helena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749977/ https://www.ncbi.nlm.nih.gov/pubmed/35008353 http://dx.doi.org/10.3390/cancers14010190

Ejemplares similares

Differences of statin activity in 2D and 3D pancreatic cancer cell cultures
por: Paškevičiūtė, Miglė, et al.
Publicado: (2017)

Recapitulating Tumor Microenvironment Using AXTEX-4D(TM) for Accelerating Cancer Research and Drug Screening
por: Baru, Ambica, et al.
Publicado: (2022)

Proton Pump Inhibitors Modulate Transport Of Doxorubicin And Its Liposomal Form Into 2D And 3D Breast Cancer Cell Cultures
por: Paškevičiūtė, Miglė, et al.
Publicado: (2019)

Comparison of NSAIDs activity in COX-2 expressing and non-expressing 2D and 3D pancreatic cancer cell cultures
por: Čeponytė, Ugnė, et al.
Publicado: (2018)

Exploration of Benzenesulfonamide-Bearing Imidazole Derivatives Activity in Triple-Negative Breast Cancer and Melanoma 2D and 3D Cell Cultures
por: Balandis, Benas, et al.
Publicado: (2021)

Evaluation of low-intensity pulsed ultrasound on doxorubicin delivery in 2D and 3D cancer cell cultures
por: Paškevičiūtė, Miglė, et al.
Publicado: (2020)

A Microdevice Platform Recapitulating Hypoxic Tumor Microenvironments
por: Ando, Yuta, et al.
Publicado: (2017)

Comparative Study of Lipophilic Statin Activity in 2D and 3D in vitro Models of Human Breast Cancer Cell Lines MDA-MB-231 and MCF-7
por: Bytautaite, Meda, et al.
Publicado: (2020)

Synergistic activity of Hsp90 inhibitors and anticancer agents in pancreatic cancer cell cultures
por: Daunys, Simonas, et al.
Publicado: (2019)

Anticancer Activity of Sunitinib Analogues in Human Pancreatic Cancer Cell Cultures under Normoxia and Hypoxia
por: Skaraitė, Ieva, et al.
Publicado: (2023)

Editorial: Hybrids Part B: Hybrids for Drug Delivery
por: Li, Wei, et al.
Publicado: (2021)

Rapid 3D bioprinting of a multicellular model recapitulating pterygium microenvironment
por: Zhong, Zheng, et al.
Publicado: (2022)

Self-Assembling Polypeptide Hydrogels as a Platform to Recapitulate the Tumor Microenvironment
por: Lachowski, Dariusz, et al.
Publicado: (2021)

Patient-derived pancreatic cancer-on-a-chip recapitulates the tumor microenvironment
por: Haque, Muhammad R., et al.
Publicado: (2022)

Bone Repair and Regenerative Biomaterials: Towards Recapitulating the Microenvironment
por: Aslankoohi, Neda, et al.
Publicado: (2019)

Modelling stromal compartments to recapitulate the ameloblastoma tumour microenvironment
por: Bakkalci, Deniz, et al.
Publicado: (2022)

Recapitulating epithelial tumor microenvironment in vitro using three dimensional tri-culture of human epithelial, endothelial, and mesenchymal cells
por: Lamichhane, Surya P., et al.
Publicado: (2016)

Recapitulating the Tumor Ecosystem Along the Metastatic Cascade Using 3D Culture Models
por: Kim, Jiyun, et al.
Publicado: (2015)

Modelling the Tumor Microenvironment: Recapitulating Nano- and Micro-Scale Properties that Regulate Tumor Progression
por: Vahala, Danielle, et al.
Publicado: (2022)

Recapitulation of Human Neural Microenvironment Signatures in iPSC-Derived NPC 3D Differentiation
por: Simão, Daniel, et al.
Publicado: (2018)

Recapitulating the Cancer Microenvironment Using Bioprinting Technology for Precision Medicine
por: Kim, Jisoo, et al.
Publicado: (2021)

Breast cancer patient-derived explant cultures recapitulate in vivo drug responses
por: Pettersen, Solveig, et al.
Publicado: (2023)

Polyurethane scaffold-based 3D lung cancer model recapitulates in vivo tumor biological behavior for nanoparticulate drug screening
por: Sun, Lu, et al.
Publicado: (2023)

Extended 2D myotube culture recapitulates postnatal fibre type plasticity
por: Sebastian, Sujith, et al.
Publicado: (2015)

Mouse Ovarian Cancer Models Recapitulate the Human Tumor Microenvironment and Patient Response to Treatment
por: Maniati, Eleni, et al.
Publicado: (2020)

Autologous humanized PDX modeling for immuno-oncology recapitulates features of the human tumor microenvironment
por: Chiorazzi, Michael, et al.
Publicado: (2023)

Recapitulated Crosstalk between Cerebral Metastatic Lung Cancer Cells and Brain Perivascular Tumor Microenvironment in a Microfluidic Co‐Culture Chip
por: Kim, Hyunho, et al.
Publicado: (2022)

Novel N-Substituted Amino Acid Hydrazone-Isatin Derivatives: Synthesis, Antioxidant Activity, and Anticancer Activity in 2D and 3D Models In Vitro
por: Tumosienė, Ingrida, et al.
Publicado: (2021)

Relationship between Antioxidant and Anticancer Activity of Trihydroxyflavones
por: Grigalius, Ignas, et al.
Publicado: (2017)

The Effect of Beta Adrenoreceptor Blockers on Viability and Cell Colony Formation of Non-Small Cell Lung Cancer Cell Lines A549 and H1299
por: Sidorova, Marina, et al.
Publicado: (2022)

Antioxidant, Anti-Inflammatory, and Cytotoxic Activity of Extracts from Some Commercial Apple Cultivars in Two Colorectal and Glioblastoma Human Cell Lines
por: Butkeviciute, Aurita, et al.
Publicado: (2021)

Patient‐derived xenograft mouse models of pseudomyxoma peritonei recapitulate the human inflammatory tumor microenvironment
por: Kuracha, Murali R., et al.
Publicado: (2016)

Modeling the tumor immune microenvironment for drug discovery using 3D culture
por: Lee, Joanna Y., et al.
Publicado: (2021)

The orthotopic xenotransplant of human glioblastoma successfully recapitulates glioblastoma-microenvironment interactions in a non-immunosuppressed mouse model
por: Garcia, Celina, et al.
Publicado: (2014)

Recapitulation
Publicado: (1866)

Recapitulation of growth factor-enriched microenvironment via BMP receptor activating hydrogel
por: Zhang, Qinghao, et al.
Publicado: (2022)

Phenolic Fractions from Vaccinium vitis-idaea L. and Their Antioxidant and Anticancer Activities Assessment
por: Vilkickyte, Gabriele, et al.
Publicado: (2020)

The Potential of Dietary Antioxidants from a Series of Plant Extracts as Anticancer Agents against Melanoma, Glioblastoma, and Breast Cancer
por: Liaudanskas, Mindaugas, et al.
Publicado: (2021)

The Chemo-Sensitizing Effect of Doxorubicin of Apple Extract-Enriched Triterpenic Complex on Human Colon Adenocarcinoma and Human Glioblastoma Cell Lines
por: Braciuliene, Aurita, et al.
Publicado: (2022)

A DNAmCULTURE Epigenetic Fingerprint Recapitulates Physiological Aging
por: Minteer, Christopher, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_s8tgcu51l2u5ofi76katdh948k