E-Cadherin-Deficient Epithelial Cells Are Sensitive to HDAC Inhibitors

SIMPLE SUMMARY: Inactivating mutations in the CDH1 gene cause the cancer syndrome hereditary diffuse gastric cancer and are also frequent in sporadic diffuse gastric and lobular breast cancers. This research aimed to test whether cancers with CDH1 mutations have heightened sensitivity to histone dea...

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Detalles Bibliográficos
Autores principales: Decourtye-Espiard, Lyvianne, Bougen-Zhukov, Nicola, Godwin, Tanis, Brew, Tom, Schulpen, Emily, Black, Michael A., Guilford, Parry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749989/
https://www.ncbi.nlm.nih.gov/pubmed/35008338
http://dx.doi.org/10.3390/cancers14010175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749989/
https://www.ncbi.nlm.nih.gov/pubmed/35008338
http://dx.doi.org/10.3390/cancers14010175

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