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E-Cadherin-Deficient Epithelial Cells Are Sensitive to HDAC Inhibitors
SIMPLE SUMMARY: Inactivating mutations in the CDH1 gene cause the cancer syndrome hereditary diffuse gastric cancer and are also frequent in sporadic diffuse gastric and lobular breast cancers. This research aimed to test whether cancers with CDH1 mutations have heightened sensitivity to histone dea...
Autores principales: | Decourtye-Espiard, Lyvianne, Bougen-Zhukov, Nicola, Godwin, Tanis, Brew, Tom, Schulpen, Emily, Black, Michael A., Guilford, Parry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749989/ https://www.ncbi.nlm.nih.gov/pubmed/35008338 http://dx.doi.org/10.3390/cancers14010175 |
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