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The Nuclear Receptor PXR in Chronic Liver Disease

Pregnane X receptor (PXR), a nuclear receptor known for modulating the transcription of drug metabolizing enzymes and transporters (DMETs), such as cytochrome P450 3A4 and P-glycoprotein, is functionally involved in chronic liver diseases of different etiologies. Furthermore, PXR activity relates to...

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Detalles Bibliográficos
Autores principales:	Sayaf, Katia, Zanotto, Ilaria, Russo, Francesco Paolo, Gabbia, Daniela, De Martin, Sara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750019/ https://www.ncbi.nlm.nih.gov/pubmed/35011625 http://dx.doi.org/10.3390/cells11010061

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