Cargando…

CXCL12 in Pancreatic Cancer: Its Function and Potential as a Therapeutic Drug Target

SIMPLE SUMMARY: Pancreatic cancer is a challenging disease to treat effectively. Fibroblasts associated with pancreatic cancer contribute to disease progression by secreting factors that enhance tumor cell survival and help tumor cells avoid detection by the immune system. This overview focuses on a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Malik, Shivani, Westcott, Jill M., Brekken, Rolf A., Burrows, Francis J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Hypothesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750050/ https://www.ncbi.nlm.nih.gov/pubmed/35008248 http://dx.doi.org/10.3390/cancers14010086

Ejemplares similares

Potential of Farnesyl Transferase Inhibitors in Combination Regimens in Squamous Cell Carcinomas
por: Kessler, Linda, et al.
Publicado: (2021)

Subunits of human condensins are potential therapeutic targets for cancers
por: Wang, Hong-Zhen, et al.
Publicado: (2018)

Potential therapeutic drug target identification in Community Acquired-Methicillin Resistant Staphylococcus aureus (CA-MRSA) using computational analysis
por: Yadav, Pramod Kumar, et al.
Publicado: (2012)

Modeling of human CCR5 as Target for HIV-I and Virtual Screening with Marine Therapeutic compounds
por: Manikandan, Selvaraj, et al.
Publicado: (2008)

Uncovering potential Drug Targets for Tuberculosis using Protein Networks
por: Raman, Mohana Priya, et al.
Publicado: (2012)

SIRT1 as a potential therapeutic target for treatment of nonalcoholic fatty liver disease
por: Colak, Yasar, et al.
Publicado: (2011)

In Silico Subtractive Proteomics Approach for Identification of Potential Drug Targets in Staphylococcus saprophyticus
por: Shahid, Farah, et al.
Publicado: (2020)

Choke point analysis of metabolic pathways in E.histolytica: A computational approach for drug target identification
por: Singh, Shailza, et al.
Publicado: (2007)

Identification of potential apicoplast associated therapeutic targets in human and animal pathogen Toxoplasma gondii ME49
por: Saremy, Sadegh, et al.
Publicado: (2011)

MicroRNAs as potential novel therapeutic targets and tools for regulating paracrine function of endothelial progenitor cells
por: Xu, Shengjie, et al.
Publicado: (2012)

Modulation of vitamin D signaling is a potential therapeutic target to lower cardiovascular risk in chronic kidney disease
por: Hu, Peng, et al.
Publicado: (2011)

Transcription Factor Nrf2 as a Potential Therapeutic Target for Prevention of Cytokine Storm in COVID-19 Patients
por: Zinovkin, R. A., et al.
Publicado: (2020)

In vitro anti-acetylcholinesterase activity of an aqueous extract of Unicaria tomentosa and in silico study of its active constituents
por: Chowdhury, Suman, et al.
Publicado: (2016)

miR-142-3p is a Potential Therapeutic Target for Sensory Function Recovery of Spinal Cord Injury
por: Wang, Tianyi, et al.
Publicado: (2015)

Dataset of potential targets for Mycobacterium tuberculosis H37Rv through comparative genome analysis
por: Asif, Siddiqui M, et al.
Publicado: (2009)

Disrupting the Balance between Tumor Epithelia and Stroma is a Possible Therapeutic Approach for Pancreatic Cancer
por: Wang, Zheng, et al.
Publicado: (2014)

Structure-based analysis of curcumin and conventionaldrugs targeting tumor-inducing protein PHF20
por: Agrawal, Vibha, et al.
Publicado: (2018)

Comparative protein modeling of spermidine synthase from Plasmodium falciparum: A potential target for anti-malarial drug therapy
por: Reddy, Duvvuru Muni Rajasekhara
Publicado: (2006)

Therapeutic Potential of Transcranial Focused Ultrasound for Rett Syndrome
por: Tsai, Shih-Jen
Publicado: (2016)

Targeting the Stromal Pro-Tumoral Hyaluronan-CD44 Pathway in Pancreatic Cancer
por: Koltai, Tomas, et al.
Publicado: (2021)

Bitter Taste Receptor as a Therapeutic Target in Orthopaedic Disorders
por: Cheng, Weyland, et al.
Publicado: (2021)

Identification and characterization of sodium and chloride-dependent gamma-aminobutyric acid (GABA) transporters from eukaryotic pathogens as a potential drug target
por: Otarigho, Benson, et al.
Publicado: (2018)

Identification & Characterization of lactobacillus salavarius bacteriocins and its relevance in cancer therapeutics
por: Shaikh, Faraz, et al.
Publicado: (2012)

Comparative analysis of human matrix metalloproteinases: Emerging therapeutic targets in diseases
por: Jaiswal, Astha, et al.
Publicado: (2011)

Alpha Satellite DNA in Targeted Drug Therapy for Prostate Cancer
por: Feliciello, Isidoro, et al.
Publicado: (2023)

Identification of miRNAs in C. roseus and their potential targets
por: Omer, Ankur, et al.
Publicado: (2012)

Metabolic abnormalities in pituitary adenoma patients: a novel therapeutic target and prognostic factor
por: Zheng, Xin, et al.
Publicado: (2015)

Selection of predicted siRNA as potential antiviral therapeutic agent against influenza virus
por: Raza, Asif, et al.
Publicado: (2011)

Does activation of the protective Renin-Angiotensin System have therapeutic potential in COVID-19?
por: Namsolleck, Pawel, et al.
Publicado: (2020)

in Silico analysis of Escherichia coli polyphosphate kinase (PPK) as a novel antimicrobial drug target and its high throughput virtual screening against PubChem library
por: Saha, Saurav Bhaskar, et al.
Publicado: (2013)

Identification and modeling of a drug target for Clostridium perfringens SM101
por: Chhabra, Gagan, et al.
Publicado: (2010)

Computational genome analyses of metabolic enzymes in Mycobacterium leprae for drug target identification
por: Shanmugam, Anusuya, et al.
Publicado: (2010)

In silico characterization of putative drug targets in Staphylococcus saprophyticus, causing bovine mastitis
por: Bhasme, Pramod C, et al.
Publicado: (2013)

Identification of neuropeptides, flp-1 and flp-12 targeting neuromuscular system of rice root knot nematode (RRKN) Meloidogyne graminicola
por: Rao, Uma, et al.
Publicado: (2013)

Virtual screening of ABCC1 transporter nucleotidebinding domains as a therapeutic target in multidrug resistant cancer
por: Rungsardthong, Kanin, et al.
Publicado: (2012)

In silico synteny based comparative genomics approach for identification and characterization of novel therapeutic targets in Chlamydophila pneumoniae
por: Ravindranath, Bilachi S, et al.
Publicado: (2013)

Proteo-transcriptomics meta-analysis identifies SUMO2 as a promising target in glioblastoma multiforme therapeutics
por: Krishna, Aswani P., et al.
Publicado: (2021)

Strategy for Pre-Clinical Development of Active Targeting MicroRNA Oligonucleotide Therapeutics for Unmet Medical Needs
por: Thibonnier, Marc, et al.
Publicado: (2023)

The Potentially Therapeutic Role of EPAC in Curbing the Process of Idiopathic Pulmonary Fibrosis via Differential Cellular Pathways
por: Cao, Xinwei, et al.
Publicado: (2021)

Computational screening of molecular targets in Plasmodium for novel non resistant anti-malarial drugs
por: Singh, Neera, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_k5ebjq2diqv67dabomr321vfkf