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Microglia-like Cells Promote Neuronal Functions in Cerebral Organoids

Human cerebral organoids, derived from induced pluripotent stem cells, offer a unique in vitro research window to the development of the cerebral cortex. However, a key player in the developing brain, the microglia, do not natively emerge in cerebral organoids. Here we show that erythromyeloid proge...

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Detalles Bibliográficos
Autores principales: Fagerlund, Ilkka, Dougalis, Antonios, Shakirzyanova, Anastasia, Gómez-Budia, Mireia, Pelkonen, Anssi, Konttinen, Henna, Ohtonen, Sohvi, Fazaludeen, Mohammad Feroze, Koskuvi, Marja, Kuusisto, Johanna, Hernández, Damián, Pebay, Alice, Koistinaho, Jari, Rauramaa, Tuomas, Lehtonen, Šárka, Korhonen, Paula, Malm, Tarja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750120/
https://www.ncbi.nlm.nih.gov/pubmed/35011686
http://dx.doi.org/10.3390/cells11010124