A Clinician’s Guide to Topical Retinoids

Retinoids are defined as molecules that bind to and activate retinoic acid receptors to influence the proliferation and differentiation of cells. Topical retinoids have evolved over the past several decades, being used in multiple dermatological conditions. This review aims to differentiate between...

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Detalles Bibliográficos
Autores principales: Motamedi, Melika, Chehade, Ahmad, Sanghera, Ravina, Grewal, Parbeer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750127/
https://www.ncbi.nlm.nih.gov/pubmed/34292058
http://dx.doi.org/10.1177/12034754211035091
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author Motamedi, Melika
Chehade, Ahmad
Sanghera, Ravina
Grewal, Parbeer
author_facet Motamedi, Melika
Chehade, Ahmad
Sanghera, Ravina
Grewal, Parbeer
author_sort Motamedi, Melika
collection PubMed
description Retinoids are defined as molecules that bind to and activate retinoic acid receptors to influence the proliferation and differentiation of cells. Topical retinoids have evolved over the past several decades, being used in multiple dermatological conditions. This review aims to differentiate between synthetic and natural retinoids, discuss the pharmacology behind topical retinoids, highlight clinical applications, and categorize all the commercially available agents, including combination products. Understanding retinoid affinities for unique receptor subtypes can impact clinical decisions, resulting in optimizing treatment and enhancing patient adherence.
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spelling pubmed-87501272022-01-12 A Clinician’s Guide to Topical Retinoids Motamedi, Melika Chehade, Ahmad Sanghera, Ravina Grewal, Parbeer J Cutan Med Surg Review Articles Retinoids are defined as molecules that bind to and activate retinoic acid receptors to influence the proliferation and differentiation of cells. Topical retinoids have evolved over the past several decades, being used in multiple dermatological conditions. This review aims to differentiate between synthetic and natural retinoids, discuss the pharmacology behind topical retinoids, highlight clinical applications, and categorize all the commercially available agents, including combination products. Understanding retinoid affinities for unique receptor subtypes can impact clinical decisions, resulting in optimizing treatment and enhancing patient adherence. SAGE Publications 2021-07-22 2022-01 /pmc/articles/PMC8750127/ /pubmed/34292058 http://dx.doi.org/10.1177/12034754211035091 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Review Articles
Motamedi, Melika
Chehade, Ahmad
Sanghera, Ravina
Grewal, Parbeer
A Clinician’s Guide to Topical Retinoids
title A Clinician’s Guide to Topical Retinoids
title_full A Clinician’s Guide to Topical Retinoids
title_fullStr A Clinician’s Guide to Topical Retinoids
title_full_unstemmed A Clinician’s Guide to Topical Retinoids
title_short A Clinician’s Guide to Topical Retinoids
title_sort clinician’s guide to topical retinoids
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750127/
https://www.ncbi.nlm.nih.gov/pubmed/34292058
http://dx.doi.org/10.1177/12034754211035091
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