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mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells

Age-related macular degeneration (AMD) is a complex degenerative disease of the retina with multiple risk-modifying factors, including aging, genetics, and lifestyle choices. The combination of these factors leads to oxidative stress, inflammation, and metabolic failure in the retinal pigment epithe...

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Detalles Bibliográficos
Autores principales: Merle, David A., Provenzano, Francesca, Jarboui, Mohamed Ali, Kilger, Ellen, Clark, Simon J., Deleidi, Michela, Armento, Angela, Ueffing, Marius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750186/
https://www.ncbi.nlm.nih.gov/pubmed/34943047
http://dx.doi.org/10.3390/antiox10121944