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Aspirin Inhibition of Group VI Phospholipase A2 Induces Synthetic Lethality in AAM Pathway Down-Regulated Gingivobuccal Squamous Carcinoma

Background: To elucidate the role of iPLA2/PLA2G6 in gingivobuccal squamous cell carcinoma (GB-SCC) and to ascertain the synthetic lethality-based chemoprevention role of aspirin in arachidonic acid metabolism (AAM) pathway down-regulated GB-SCC. Methods: The in vitro efficacy of aspirin on GB-SCC c...

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Detalles Bibliográficos
Autores principales:	Pansare, Kshama, Mohanty, Bhabani, Dhotre, Ranjeeta, Pettiwala, Aafrin M., Parab, Saili, Gupta, Neha, Gera, Poonam, Gardi, Nilesh, Dugge, Rucha, Sahu, Priyanka, Alhans, Ruby, Kowtal, Pradnya, Chaudhari, Pradip, Sarin, Rajiv
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750243/ https://www.ncbi.nlm.nih.gov/pubmed/35011685 http://dx.doi.org/10.3390/cells11010123

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