The Tumour Suppressor CYLD Is Required for Clathrin-Mediated Endocytosis of EGFR and Cetuximab-Induced Apoptosis in Head and Neck Squamous Cell Carcinoma

SIMPLE SUMMARY: Epidermal growth factor receptor (EGFR) is a target for the therapeutic antibody cetuximab (CTX) in head and neck squamous cell carcinoma (HNSCC). Identification of its predictive biomarkers and potentiation of CTX-based therapies are important. In this study, we found that the N-ter...

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Detalles Bibliográficos
Autores principales: Liu, Rin, Shinriki, Satoru, Maeshiro, Manabu, Hirayama, Mayumi, Jono, Hirofumi, Yoshida, Ryoji, Nakayama, Hideki, Matsui, Hirotaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750287/
https://www.ncbi.nlm.nih.gov/pubmed/35008337
http://dx.doi.org/10.3390/cancers14010173

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