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Bicarbonate Transport in Cystic Fibrosis and Pancreatitis

CFTR, the cystic fibrosis (CF) gene-encoded epithelial anion channel, has a prominent role in driving chloride, bicarbonate and fluid secretion in the ductal cells of the exocrine pancreas. Whereas severe mutations in CFTR cause fibrosis of the pancreas in utero, CFTR mutants with residual function,...

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Detalles Bibliográficos
Autores principales: Angyal, Dora, Bijvelds, Marcel J. C., Bruno, Marco J., Peppelenbosch, Maikel P., de Jonge, Hugo R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750324/
https://www.ncbi.nlm.nih.gov/pubmed/35011616
http://dx.doi.org/10.3390/cells11010054