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Arterial Administration of DNA Crosslinking Agents with Restraint of Homologous Recombination Repair by Intravenous Low-Dose Gemcitabine Is Effective for Locally Advanced Pancreatic Cancer

SIMPLE SUMMARY: Pancreatic cancer is considered incurable, and most cases are detected in the advanced stages. Establishing a new, effective interventional treatment for advanced pancreatic cancer is a pressing issue. Pretreatment with gemcitabine had a restraining effect on the homologous DNA recom...

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Detalles Bibliográficos
Autores principales: Mori, Hiromu, Tanoue, Shuichi, Takaji, Ryo, Ueda, Shinya, Okahara, Mika, Ueda, Saori Sugi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750330/
https://www.ncbi.nlm.nih.gov/pubmed/35008384
http://dx.doi.org/10.3390/cancers14010220