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RhoGDI2-Mediated Rac1 Recruitment to Filamin A Enhances Rac1 Activity and Promotes Invasive Abilities of Gastric Cancer Cells

SIMPLE SUMMARY: Rho GDP dissociation inhibitor 2 (RhoGDI2), a regulator of Rho family GTPase, has been known to promote tumor growth and malignant progression by activating Rac1 in gastric cancer. However, the precise molecular mechanism by which RhoGDI2 activates Rac1 in gastric cancer cells remain...

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Detalles Bibliográficos
Autores principales:	Kim, Hyo-Jin, Ryu, Ki-Jun, Kim, Minju, Kim, Taeyoung, Kim, Seon-Hee, Han, Hyeontak, Kim, Hyemin, Hong, Keun-Seok, Song, Chae Yeong, Choi, Yeonga, Hwangbo, Cheol, Kim, Kwang Dong, Yoo, Jiyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750349/ https://www.ncbi.nlm.nih.gov/pubmed/35008419 http://dx.doi.org/10.3390/cancers14010255

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