Cargando…

The Anti-Inflammatory Effect of the β1-Adrenergic Receptor Antagonist Metoprolol on High Glucose Treated Human Microvascular Retinal Endothelial Cells

Hyperglycemia-induced impairment of the blood-retinal barrier represents the main pathological event in diabetic retinopathy that is elicited by a reduced cellular response to an accumulation of reactive oxygen species (ROS) and increased inflammation. The purpose of the study was to evaluate whethe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Giurdanella, Giovanni, Longo, Anna, Distefano, Alfio, Olivieri, Melania, Cristaldi, Martina, Cosentino, Alessia, Agafonova, Aleksandra, Caporarello, Nunzia, Lupo, Gabriella, Anfuso, Carmelina Daniela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750370/ https://www.ncbi.nlm.nih.gov/pubmed/35011613 http://dx.doi.org/10.3390/cells11010051

Ejemplares similares

[Corrigendum] Melanogenesis in uveal melanoma cells: Effect of argan oil
por: Caporarello, Nunzia, et al.
Publicado: (2023)

Classical VEGF, Notch and Ang signalling in cancer angiogenesis, alternative approaches and future directions
por: Caporarello, Nunzia, et al.
Publicado: (2017)

Anti‐angiogenic effect of quercetin and its 8‐methyl pentamethyl ether derivative in human microvascular endothelial cells
por: Lupo, Gabriella, et al.
Publicado: (2019)

Anti-angiogenic Therapy in Cancer: Downsides and New Pivots for Precision Medicine
por: Lupo, Gabriella, et al.
Publicado: (2017)

Pericytes of Stria Vascularis Are Targets of Cisplatin-Induced Ototoxicity: New Insights into the Molecular Mechanisms Involved in Blood-Labyrinth Barrier Breakdown
por: Anfuso, Carmelina Daniela, et al.
Publicado: (2022)

Cytosolic and Calcium-Independent Phospholipases A(2) Activation and Prostaglandins E(2) Are Associated with Escherichia coli-Induced Reduction of Insulin Secretion in INS-1E Cells
por: Caporarello, Nunzia, et al.
Publicado: (2016)

Uveal Melanoma Cells Elicit Retinal Pericyte Phenotypical and Biochemical Changes in an in Vitro Model of Coculture
por: Anfuso, Carmelina Daniela, et al.
Publicado: (2020)

Atropine Differentially Modulates ECM Production by Ocular Fibroblasts, and Its Ocular Surface Toxicity Is Blunted by Colostrum
por: Cristaldi, Martina, et al.
Publicado: (2020)

Protective Effects of Human Pericyte-like Adipose-Derived Mesenchymal Stem Cells on Human Retinal Endothelial Cells in an In Vitro Model of Diabetic Retinopathy: Evidence for Autologous Cell Therapy
por: Lupo, Gabriella, et al.
Publicado: (2023)

Pericytes in Microvessels: From “Mural” Function to Brain and Retina Regeneration
por: Caporarello, Nunzia, et al.
Publicado: (2019)

Immobilization of Neurotrophin Peptides on Gold Nanoparticles by Direct and Lipid-Mediated Interaction: A New Multipotential Therapeutic Nanoplatform for CNS Disorders
por: Di Pietro, Patrizia, et al.
Publicado: (2017)

Glucose-Impaired Corneal Re-Epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate
por: Giurdanella, Giovanni, et al.
Publicado: (2021)

Effects of High Glucose Concentration on Pericyte-Like Differentiated Human Adipose-Derived Mesenchymal Stem Cells
por: Mannino, Giuliana, et al.
Publicado: (2021)

Potential therapeutic applications of mesenchymal stem cells for the treatment of eye diseases
por: Mannino, Giuliana, et al.
Publicado: (2021)

Vitamin D(3) preserves blood retinal barrier integrity in an in vitro model of diabetic retinopathy
por: Lazzara, Francesca, et al.
Publicado: (2022)

Gabapentin Attenuates Ocular Inflammation: In vitro and In vivo Studies
por: Anfuso, Carmelina D., et al.
Publicado: (2017)

Differential effects of adrenergic antagonists (Carvedilol vs Metoprolol) on parasympathetic and sympathetic activity: a comparison of measures
por: Vinik, Aaron I., et al.
Publicado: (2014)

Differential effects of adrenergic antagonists (Carvedilol vs Metoprolol) on parasympathetic and sympathetic activity: a comparison of clinical results
por: Bloom, Heather L., et al.
Publicado: (2014)

Effect of adrenergic blockers, carvedilol, prazosin, metoprolol and combination of prazosin and metoprolol on paracetamol-induced hepatotoxicity in rabbits
por: Zubairi, Maysaa B., et al.
Publicado: (2014)

Activation of the VEGF-A/ERK/PLA2 Axis Mediates Early Retinal Endothelial Cell Damage Induced by High Glucose: New Insight from an In Vitro Model of Diabetic Retinopathy
por: Giurdanella, Giovanni, et al.
Publicado: (2020)

Antiproliferative and Antiangiogenic Effects of Punica granatum Juice (PGJ) in Multiple Myeloma (MM)
por: Tibullo, Daniele, et al.
Publicado: (2016)

Haloperidol Metabolite II Valproate Ester (S)-(−)-MRJF22: Preliminary Studies as a Potential Multifunctional Agent Against Uveal Melanoma
por: Barbaraci, Carla, et al.
Publicado: (2021)

Ferulic Acid-Loaded Polymeric Nanoparticles for Potential Ocular Delivery
por: Romeo, Alessia, et al.
Publicado: (2021)

Anti-Angiogenic and Anti-Proliferative Graphene Oxide Nanosheets for Tumor Cell Therapy
por: Verde, Valeria, et al.
Publicado: (2020)

Beta adrenergic antagonists and antianginal drugs
por: Stever, Lindsey M., et al.
Publicado: (2021)

Downregulation of the β1 adrenergic receptor in the myocardium results in insensitivity to metoprolol and reduces blood pressure in spontaneously hypertensive rats
por: Huang, Yun, et al.
Publicado: (2017)

Identification of novel chemotherapeutic strategies for metastatic uveal melanoma
por: Fagone, Paolo, et al.
Publicado: (2017)

A Tunable Nanoplatform of Nanogold Functionalised with Angiogenin Peptides for Anti-Angiogenic Therapy of Brain Tumours
por: Naletova, Irina, et al.
Publicado: (2019)

Beta-Adrenergic Antagonist Tolerance in Amyloid Cardiomyopathy
por: Ramsell, Stuart, et al.
Publicado: (2022)

Impact of amiodarone use on metoprolol concentrations, α‐OH‐metoprolol concentrations, metoprolol dosing and heart rate: A cross‐sectional study
por: Robert, Sabrina, et al.
Publicado: (2023)

Health expenditure comparison of extended-release metoprolol succinate and immediate-release metoprolol tartarate
por: Vaidya, Varun, et al.
Publicado: (2012)

Identification of Novel MicroRNAs and Their Diagnostic and Prognostic Significance in Oral Cancer
por: Falzone, Luca, et al.
Publicado: (2019)

Mitochondrial Disorder Aggravated by Metoprolol
por: Samuels, Cheryl, et al.
Publicado: (2016)

Discontinuation and dose adjustment of metoprolol after metoprolol‐paroxetine/fluoxetine co‐prescription in Dutch elderly
por: Bahar, Muh. Akbar, et al.
Publicado: (2018)

324 The role of CCN3 in lung endothelial identity and function
por: Betageri, Kalpana, et al.
Publicado: (2022)

Interaction between Antagonist of Cannabinoid Receptor and Antagonist of Adrenergic Receptor on Anxiety in Male Rat
por: Komaki, Alireza, et al.
Publicado: (2014)

Prognostic significance of deregulated microRNAs in uveal melanomas
por: Falzone, Luca, et al.
Publicado: (2019)

Beta-adrenergic receptor antagonists and chronic heart failure in children
por: Filippo, Sylvie Di
Publicado: (2007)

QSPR analysis of some agonists and antagonists of α-adrenergic receptors
por: Kawczak, Piotr, et al.
Publicado: (2014)

METOPROLOL IN MANAGEMENT OF PATIENTS WITH DEPRESSION AND HYPERTENSION
por: Chaturvedi, S.K.
Publicado: (1986)

Cannot write session to /tmp/vufind_sessions/sess_v4s0hq0vqi7bi5in1s15mg0kb5