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A Gene Signature Derived from the Loss of CDKN1A (p21) Is Associated with CMS4 Colorectal Cancer

SIMPLE SUMMARY: A gene signature derived from the loss of CDKN1A (p21) gene, obtained in HCT116 p21-/- colorectal cancer cells, is identified in a large cohort of primary colorectal (CRC) tumors and is associated with the Consensus Molecular Subtype (CMS) of colon cancer that has a worse relapse-fre...

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Detalles Bibliográficos
Autores principales:	Bueno-Fortes, Santiago, Muenzner, Julienne K., Berral-Gonzalez, Alberto, Hampel, Chuanpit, Lindner, Pablo, Berninger, Alexandra, Huebner, Kerstin, Kunze, Philipp, Bäuerle, Tobias, Erlenbach-Wuensch, Katharina, Sánchez-Santos, José Manuel, Hartmann, Arndt, De Las Rivas, Javier, Schneider-Stock, Regine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750372/ https://www.ncbi.nlm.nih.gov/pubmed/35008299 http://dx.doi.org/10.3390/cancers14010136

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