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Intracellular Amplifiers of Reactive Oxygen Species Affecting Mitochondria as Radiosensitizers

SIMPLE SUMMARY: Prodrugs that increase the level of reactive oxygen species (ROS) specifically in cancer cells while not affecting normal cells can potentially act as radiosensitizers for side effect free radiotherapy (RT). However, previously known ROS-amplifying prodrugs were found to not beuseful...

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Detalles Bibliográficos
Autores principales:	Xu, Hong-Gui, Reshetnikov, Viktor, Wondrak, Marit, Eckhardt, Lisa, Kunz-Schughart, Leoni A., Janko, Christina, Tietze, Rainer, Alexiou, Christoph, Borchardt, Hannes, Aigner, Achim, Gong, Wenjie, Schmitt, Michael, Sellner, Leopold, Daum, Steffen, Özkan, Hülya Gizem, Mokhir, Andriy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750417/ https://www.ncbi.nlm.nih.gov/pubmed/35008371 http://dx.doi.org/10.3390/cancers14010208

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