Cargando…
Ginsenoside Rg3 Attenuates TNF-α-Induced Damage in Chondrocytes through Regulating SIRT1-Mediated Anti-Apoptotic and Anti-Inflammatory Mechanisms
The upregulation of tumor necrosis factor-alpha (TNF-α) is a common event in arthritis, and the subsequent signaling cascade that leads to tissue damage has become the research focus. To explore a potential therapeutic strategy to prevent cartilage degradation, we tested the effect of ginsenoside Rg...
Autores principales: | Ma, Ching-Hou, Chou, Wan-Ching, Wu, Chin-Hsien, Jou, I-Ming, Tu, Yuan-Kun, Hsieh, Pei-Ling, Tsai, Kun-Ling |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750552/ https://www.ncbi.nlm.nih.gov/pubmed/34943075 http://dx.doi.org/10.3390/antiox10121972 |
Ejemplares similares
-
Homocysteine causes dysfunction of chondrocytes and oxidative stress through repression of SIRT1/AMPK pathway: A possible link between hyperhomocysteinemia and osteoarthritis
por: Ma, Ching-Hou, et al.
Publicado: (2018) -
PKR Promotes Oxidative Stress and Apoptosis of Human Articular Chondrocytes by Causing Mitochondrial Dysfunction through p38 MAPK Activation—PKR Activation Causes Apoptosis in Human Chondrocytes
por: Ma, Ching-Hou, et al.
Publicado: (2019) -
PKR activation causes inflammation and MMP-13 secretion in human degenerated articular chondrocytes
por: Ma, Ching-Hou, et al.
Publicado: (2017) -
Anti-Angiogenic Properties of Ginsenoside Rg3
por: Nakhjavani, Maryam, et al.
Publicado: (2020) -
The Anti-Tumor Effect and Underlying Apoptotic Mechanism of Ginsenoside Rk1 and Rg5 in Human Liver Cancer Cells
por: Chen, Chen, et al.
Publicado: (2021)