Activation of the Unfolded Protein Response (UPR) Is Associated with Cholangiocellular Injury, Fibrosis and Carcinogenesis in an Experimental Model of Fibropolycystic Liver Disease

SIMPLE SUMMARY: Polycystic liver disease (PLD) is a group of rare disorders that result from structural changes in the biliary tree development in the liver. In the present work, we studied alterations in molecular mechanisms and signaling pathways that might be responsible for these pathologies. We...

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Detalles Bibliográficos
Autores principales: Chen, Chaobo, Wu, Hanghang, Ye, Hui, Tortajada, Agustín, Rodríguez-Perales, Sandra, Torres-Ruiz, Raúl, Vidal, August, Peligros, Maria Isabel, Reissing, Johanna, Bruns, Tony, Mohamed, Mohamed Ramadan, Zheng, Kang, Lujambio, Amaia, Iraburu, Maria J., Colyn, Leticia, Latasa, Maria Ujue, Arechederra, María, Fernández-Barrena, Maite G., Berasain, Carmen, Vaquero, Javier, Bañares, Rafael, Nelson, Leonard J., Trautwein, Christian, Davis, Roger J., Martinez-Naves, Eduardo, Nevzorova, Yulia A., Villanueva, Alberto, Avila, Matias A., Cubero, Francisco Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750579/
https://www.ncbi.nlm.nih.gov/pubmed/35008241
http://dx.doi.org/10.3390/cancers14010078

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