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Targeted Disruption of E6/p53 Binding Exerts Broad Activity and Synergism with Paclitaxel and Topotecan against HPV-Transformed Cancer Cells

SIMPLE SUMMARY: The identification of new specific anti-human papillomavirus (HPV) drugs is highly needed, as HPV-induced cancers still represent a significant medical issue. The aim of this study was to analyze in more detail the therapeutic potential of a compound, Cpd12, that acts by blocking the...

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Detalles Bibliográficos
Autores principales: Celegato, Marta, Messa, Lorenzo, Bertagnin, Chiara, Mercorelli, Beatrice, Loregian, Arianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750593/
https://www.ncbi.nlm.nih.gov/pubmed/35008354
http://dx.doi.org/10.3390/cancers14010193