Cargando…
Targeted Disruption of E6/p53 Binding Exerts Broad Activity and Synergism with Paclitaxel and Topotecan against HPV-Transformed Cancer Cells
SIMPLE SUMMARY: The identification of new specific anti-human papillomavirus (HPV) drugs is highly needed, as HPV-induced cancers still represent a significant medical issue. The aim of this study was to analyze in more detail the therapeutic potential of a compound, Cpd12, that acts by blocking the...
Autores principales: | Celegato, Marta, Messa, Lorenzo, Bertagnin, Chiara, Mercorelli, Beatrice, Loregian, Arianna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750593/ https://www.ncbi.nlm.nih.gov/pubmed/35008354 http://dx.doi.org/10.3390/cancers14010193 |
Ejemplares similares
-
A quantitative LumiFluo assay to test inhibitory compounds blocking p53 degradation induced by human papillomavirus oncoprotein E6 in living cells
por: Messa, Lorenzo, et al.
Publicado: (2018) -
The Dimeric Form of HPV16 E6 Is Crucial to Drive YAP/TAZ Upregulation through the Targeting of hScrib
por: Messa, Lorenzo, et al.
Publicado: (2021) -
Small-Molecule Inhibitor of Flaviviral NS3-NS5 Interaction with Broad-Spectrum Activity and Efficacy In Vivo
por: Celegato, Marta, et al.
Publicado: (2023) -
Drug Repurposing for Viral Infectious Diseases: How Far Are We?
por: Mercorelli, Beatrice, et al.
Publicado: (2018) -
Early inhibitors of human cytomegalovirus: State-of-art and therapeutic perspectives
por: Mercorelli, Beatrice, et al.
Publicado: (2011)