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Older adults mount less durable humoral responses to two doses of COVID-19 mRNA vaccine, but strong initial responses to a third dose
BACKGROUND: Third COVID-19 vaccine doses are broadly recommended, but immunogenicity data remain limited, particularly in older adults. METHODS: We measured circulating antibodies against the SARS-CoV-2 spike protein receptor-binding domain, ACE2 displacement, and virus neutralization against ancest...
Autores principales: | Mwimanzi, Francis, Lapointe, Hope R., Cheung, Peter K., Sang, Yurou, Yaseen, Fatima, Umviligihozo, Gisele, Kalikawe, Rebecca, Datwani, Sneha, Omondi, F. Harrison, Burns, Laura, Young, Landon, Leung, Victor, Agafitei, Olga, Ennis, Siobhan, Dong, Winnie, Basra, Simran, Lim, Li Yi, Ng, Kurtis, Pantophlet, Ralph, Brumme, Chanson J., Montaner, Julio S.G., Prystajecky, Natalie, Lowe, Christopher F., DeMarco, Mari L., Holmes, Daniel T., Simons, Janet, Niikura, Masahiro, Romney, Marc G., Brumme, Zabrina L., Brockman, Mark A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750654/ https://www.ncbi.nlm.nih.gov/pubmed/35018381 http://dx.doi.org/10.1101/2022.01.06.22268745 |
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