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LRRK2 at Striatal Synapses: Cell-Type Specificity and Mechanistic Insights

Mutations in leucine-rich repeat kinase 2 (LRRK2) cause Parkinson’s disease with a similar clinical presentation and progression to idiopathic Parkinson’s disease, and common variation is linked to disease risk. Recapitulation of the genotype in rodent models causes abnormal dopamine release and inc...

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Detalles Bibliográficos
Autores principales: Skelton, Patrick D., Tokars, Valerie, Parisiadou, Loukia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750662/
https://www.ncbi.nlm.nih.gov/pubmed/35011731
http://dx.doi.org/10.3390/cells11010169