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LRRK2 at Striatal Synapses: Cell-Type Specificity and Mechanistic Insights
Mutations in leucine-rich repeat kinase 2 (LRRK2) cause Parkinson’s disease with a similar clinical presentation and progression to idiopathic Parkinson’s disease, and common variation is linked to disease risk. Recapitulation of the genotype in rodent models causes abnormal dopamine release and inc...
Autores principales: | Skelton, Patrick D., Tokars, Valerie, Parisiadou, Loukia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750662/ https://www.ncbi.nlm.nih.gov/pubmed/35011731 http://dx.doi.org/10.3390/cells11010169 |
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