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Role of Human Antigen R (HuR) in the Regulation of Pulmonary ACE2 Expression

Patients with COPD may be at an increased risk for severe illness from COVID-19 because of ACE2 upregulation, the entry receptor for SARS-CoV-2. Chronic exposure to cigarette smoke, the main risk factor for COPD, increases pulmonary ACE2. How ACE2 expression is controlled is not known but may involv...

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Detalles Bibliográficos
Autores principales: Aloufi, Noof, Haidar, Zahraa, Ding, Jun, Nair, Parameswaran, Benedetti, Andrea, Eidelman, David H., Gallouzi, Imed-Eddine, Di Marco, Sergio, Hussain, Sabah N., Baglole, Carolyn J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750694/
https://www.ncbi.nlm.nih.gov/pubmed/35011584
http://dx.doi.org/10.3390/cells11010022