Vaccines Elicit Highly Cross-Reactive Cellular Immunity to the SARS-CoV-2 Omicron Variant

The highly mutated SARS-CoV-2 Omicron (B.1.1.529) variant has been shown to evade a substantial fraction of neutralizing antibody responses elicited by current vaccines that encode the WA1/2020 Spike immunogen(1), resulting in increased breakthrough infections and reduced vaccine efficacy. Cellular...

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Detalles Bibliográficos
Autores principales: Liu, Jinyan, Chandrashekar, Abishek, Sellers, Daniel, Barrett, Julia, Lifton, Michelle, McMahan, Katherine, Sciacca, Michaela, VanWyk, Haley, Wu, Cindy, Yu, Jingyou, Collier, Ai-ris Y., Barouch, Dan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750713/
https://www.ncbi.nlm.nih.gov/pubmed/35018387
http://dx.doi.org/10.1101/2022.01.02.22268634

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