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Structural Aspects of LIMK Regulation and Pharmacology

Malfunction of the actin cytoskeleton is linked to numerous human diseases including neurological disorders and cancer. LIMK1 (LIM domain kinase 1) and its paralogue LIMK2 are two closely related kinases that control actin cytoskeleton dynamics. Consequently, they are potential therapeutic targets f...

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Detalles Bibliográficos
Autores principales:	Chatterjee, Deep, Preuss, Franziska, Dederer, Verena, Knapp, Stefan, Mathea, Sebastian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750758/ https://www.ncbi.nlm.nih.gov/pubmed/35011704 http://dx.doi.org/10.3390/cells11010142

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