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IL-10 Rescues CLL Survival through Repolarization of Inflammatory Nurse-like Cells

SIMPLE SUMMARY: In in vitro co-cultures of CLL cells and nurse-like cells (NLC), protection against apoptosis is only provided by M2-like NLC, and not M1-like NLC. In this study, we propose that fine-tuning of NLC polarization (and therefore survival of leukemic cells) is dictated by a balance betwe...

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Detalles Bibliográficos
Autores principales: Domagala, Marcin, Ysebaert, Loïc, Ligat, Laetitia, Lopez, Frederic, Fournié, Jean-Jacques, Laurent, Camille, Poupot, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750769/
https://www.ncbi.nlm.nih.gov/pubmed/35008174
http://dx.doi.org/10.3390/cancers14010016