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Metabolic Implications of Immune Checkpoint Proteins in Cancer

Expression of immune checkpoint proteins restrict immunosurveillance in the tumor microenvironment; thus, FDA-approved checkpoint inhibitor drugs, specifically PD-1/PD-L1 and CTLA-4 inhibitors, promote a cytotoxic antitumor immune response. Aside from inflammatory signaling, immune checkpoint protei...

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Detalles Bibliográficos
Autores principales:	Stirling, Elizabeth R., Bronson, Steven M., Mackert, Jessica D., Cook, Katherine L., Triozzi, Pierre L., Soto-Pantoja, David R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750774/ https://www.ncbi.nlm.nih.gov/pubmed/35011741 http://dx.doi.org/10.3390/cells11010179

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