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A novel nonparametric computational strategy for identifying differential methylation regions
BACKGROUND: DNA methylation has long been known as an epigenetic gene silencing mechanism. For a motivating example, the methylomes of cancer and non-cancer cells show a number of methylation differences, indicating that certain features characteristics of cancer cells may be related to methylation...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750844/ https://www.ncbi.nlm.nih.gov/pubmed/35012449 http://dx.doi.org/10.1186/s12859-022-04563-8 |