Vaccine Based on Dendritic Cells Electroporated with an Exogenous Ovalbumin Protein and Pulsed with Invariant Natural Killer T Cell Ligands Effectively Induces Antigen-Specific Antitumor Immunity

SIMPLE SUMMARY: This study shows the potential of a novel dendritic cell vaccine therapy in antitumor immunity, in which bone marrow-derived dendritic cells are electroporated with an exogenous ovalbumin protein and simultaneously pulsed with α-galactosylceramide. This strategy enhances the inductio...

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Detalles Bibliográficos
Autores principales: Watanabe, Akihiro, Yamashita, Kimihiro, Fujita, Mitsugu, Arimoto, Akira, Nishi, Masayasu, Takamura, Shiki, Saito, Masafumi, Yamada, Kota, Agawa, Kyosuke, Mukoyama, Tomosuke, Ando, Masayuki, Kanaji, Shingo, Matsuda, Takeru, Oshikiri, Taro, Kakeji, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750915/
https://www.ncbi.nlm.nih.gov/pubmed/35008335
http://dx.doi.org/10.3390/cancers14010171

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