Cargando…

Lysyl-Oxidase Dependent Extracellular Matrix Stiffness in Hodgkin Lymphomas: Mechanical and Topographical Evidence

SIMPLE SUMMARY: Alterations of the composition and architecture of the extracellular matrix (ECM), leading to increased stiffness, is known to condition development, invasiveness and severity of neoplasms. In this study, we report increased lymph node (LN) stiffness in human lymphomas, measured by L...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alfano, Massimo, Locatelli, Irene, D’Arrigo, Cristina, Mora, Marco, Vozzi, Giovanni, De Acutis, Aurora, Pece, Roberta, Tavella, Sara, Costa, Delfina, Poggi, Alessandro, Zocchi, Maria Raffaella
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750937/ https://www.ncbi.nlm.nih.gov/pubmed/35008423 http://dx.doi.org/10.3390/cancers14010259

Ejemplares similares

Inhibitors of ADAM10 reduce Hodgkin lymphoma cell growth in 3D microenvironments and enhance brentuximab-vedotin effect
por: Pece, Roberta, et al.
Publicado: (2021)

The Interactome of Cancer-Related Lysyl Oxidase and Lysyl Oxidase-Like Proteins
por: Vallet, Sylvain D., et al.
Publicado: (2020)

Multifunctional Lysyl Oxidases
por: Trackman, Philip C.
Publicado: (2023)

Specific ADAM10 inhibitors localize in exosome-like vesicles released by Hodgkin lymphoma and stromal cells and prevent sheddase activity carried to bystander cells
por: Tosetti, Francesca, et al.
Publicado: (2018)

Effect of Lysyl Oxidase Inhibition on Angiotensin II-Induced Arterial Hypertension, Remodeling, and Stiffness
por: Eberson, Lance S., et al.
Publicado: (2015)

Origin and evolution of lysyl oxidases
por: Grau-Bové, Xavier, et al.
Publicado: (2015)

Lysyl Oxidase and the Tumor Microenvironment
por: Wang, Tong-Hong, et al.
Publicado: (2016)

Arterial stiffness and cardiac dysfunction in Hutchinson–Gilford Progeria Syndrome corrected by inhibition of lysyl oxidase
por: von Kleeck, Ryan, et al.
Publicado: (2021)

How to exploit stress-related immunity against Hodgkin’s lymphoma: Targeting ERp5 and ADAM sheddases
por: Poggi, Alessandro, et al.
Publicado: (2013)

Priming of Colorectal Tumor-Associated Fibroblasts with Zoledronic Acid Conjugated to the Anti-Epidermal Growth Factor Receptor Antibody Cetuximab Elicits Anti-Tumor Vδ2 T Lymphocytes
por: Fernandez, Jordi Leonardo Castrillo, et al.
Publicado: (2023)

Lysyl Oxidase Polymorphisms and Susceptibility to Osteosarcoma
por: Liu, Yang, et al.
Publicado: (2012)

An in situ activity assay for lysyl oxidases
por: Wang, Huilei, et al.
Publicado: (2021)

Serum Lysyl Oxidase Levels and Lysyl Oxidase Gene Polymorphism in Ovarian Cancer Patients of Eastern Indian Population
por: Kumari, Suchitra, et al.
Publicado: (2021)

Overhydroxylation of Lysine of Collagen Increases Uterine Fibroids Proliferation: Roles of Lysyl Hydroxylases, Lysyl Oxidases, and Matrix Metalloproteinases
por: Kamel, Marwa, et al.
Publicado: (2017)

Serum lysyl oxidase concentration increases in long-standing systemic sclerosis: Can lysyl oxidase change over time?
por: Jokar, Mohammad Hassan, et al.
Publicado: (2021)

Knock-Out of the Five Lysyl-Oxidase Family Genes Enables Identification of Lysyl-Oxidase Pro-Enzyme Regulated Genes
por: Liburkin-Dan, Tatyana, et al.
Publicado: (2022)

Erratum to “Overhydroxylation of Lysine of Collagen Increases Uterine Fibroids Proliferation: Roles of Lysyl Hydroxylases, Lysyl Oxidases, and Matrix Metalloproteinases”
por: Kamel, Marwa, et al.
Publicado: (2018)

Targeting lysyl oxidase reduces peritoneal fibrosis
por: Harlow, Christopher R., et al.
Publicado: (2017)

Fibrosis in Mesothelioma: Potential Role of Lysyl Oxidases
por: Perryman, Lara, et al.
Publicado: (2022)

Retraction: Lysyl Oxidase Polymorphisms and Susceptibility to Osteosarcoma
Publicado: (2022)

Inhibition of Lysyl Oxidase and Lysyl Oxidase-Like Enzymes Has Tumour-Promoting and Tumour-Suppressing Roles in Experimental Prostate Cancer
por: Nilsson, Maria, et al.
Publicado: (2016)

Effect of Lysyl Oxidase G473A Polymorphism on Lysyl Oxidase and Total Soluble Collagen Expression in Oral Submucous Fibrosis
por: Mukherjee, Sanjit, et al.
Publicado: (2021)

The role of lysyl oxidase, the extracellular matrix and the pre-metastatic niche in bone metastasis()()
por: Gartland, Alison, et al.
Publicado: (2016)

Collagen cross-links scale with passive stiffness in dystrophic mouse muscles, but are not altered with administration of a lysyl oxidase inhibitor
por: Brashear, Sarah E., et al.
Publicado: (2022)

Ultrastructural immunolocalization of lysyl oxidase in vascular connective tissue
Publicado: (1986)

Targeting lysyl oxidase for molecular imaging in breast cancer
por: Wuest, Melinda, et al.
Publicado: (2015)

Lysyl oxidase family members in urological tumorigenesis and fibrosis
por: Li, Tao, et al.
Publicado: (2018)

Role of the lysyl oxidase family in organ development (Review)
por: Wei, Shanzun, et al.
Publicado: (2020)

Lysyl Oxidase (LOX): Functional Contributions to Signaling Pathways
por: Laczko, Rozalia, et al.
Publicado: (2020)

Lysyl oxidases: linking structures and immunity in the tumor microenvironment
por: Tenti, Paolo, et al.
Publicado: (2019)

The Role of Lysyl Oxidase Enzymes in Cardiac Function and Remodeling
por: Rodríguez, Cristina, et al.
Publicado: (2019)

Molecular Insights Into Lysyl Oxidases in Cartilage Regeneration and Rejuvenation
por: Lin, Weiping, et al.
Publicado: (2020)

The prognostic value of the lysyl oxidase family in ovarian cancer
por: Ye, Miaomiao, et al.
Publicado: (2020)

Author Correction: An in situ activity assay for lysyl oxidases
por: Wang, Huilei, et al.
Publicado: (2021)

The Expression Patterns and Roles of Lysyl Oxidases in Aortic Dissection
por: Yi, Xin, et al.
Publicado: (2021)

Lysyl Oxidase Family Enzymes and Their Role in Tumor Progression
por: Liburkin-Dan, Tanya, et al.
Publicado: (2022)

Mechanistic insight into lysyl oxidase in vascular remodeling and angiogenesis
por: Wang, Zhao-Jun, et al.
Publicado: (2022)

Downregulation of lysyl oxidase and lysyl oxidase-like protein 2 suppressed the migration and invasion of trophoblasts by activating the TGF-β/collagen pathway in preeclampsia
por: Xu, Xiang-Hong, et al.
Publicado: (2019)

Effect of Anti-Hypertensive Medication on Plasma Concentrations of Lysyl Oxidase: Evidence for Aldosterone-IL-6-Dependent Regulation of Lysyl Oxidase Blood Concentration
por: Schreckenberg, Rolf, et al.
Publicado: (2022)

ADAM10 new selective inhibitors reduce NKG2D ligand release sensitizing Hodgkin lymphoma cells to NKG2D-mediated killing
por: Zocchi, Maria Raffaella, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_trboihq0eemlv1td4j9vkbgt56