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The evaluation of cytotoxicity and cytokine IL-6 production of root canal sealers with and without the incorporation of simvastatin: an invitro study

BACKGROUND: Freshly mixed root canal sealers when proximate the periapical tissues, trigger varying degrees of cytotoxicity/inflammatory reactions. Simvastatin, a class of the drug statin, is a widely used cholesterol-lowering agent with additional anti-inflammatory activities. This study assessed t...

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Detalles Bibliográficos
Autores principales: Sharma, Apoorva, Sanjeev, Kavitha, Selvanathan, Vinola M. J., Sekar, Mahalaxmi, Harikrishnan, Nikhil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751161/
https://www.ncbi.nlm.nih.gov/pubmed/35012572
http://dx.doi.org/10.1186/s12903-022-02039-y