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The evaluation of cytotoxicity and cytokine IL-6 production of root canal sealers with and without the incorporation of simvastatin: an invitro study
BACKGROUND: Freshly mixed root canal sealers when proximate the periapical tissues, trigger varying degrees of cytotoxicity/inflammatory reactions. Simvastatin, a class of the drug statin, is a widely used cholesterol-lowering agent with additional anti-inflammatory activities. This study assessed t...
Autores principales: | Sharma, Apoorva, Sanjeev, Kavitha, Selvanathan, Vinola M. J., Sekar, Mahalaxmi, Harikrishnan, Nikhil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751161/ https://www.ncbi.nlm.nih.gov/pubmed/35012572 http://dx.doi.org/10.1186/s12903-022-02039-y |
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