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UM171A-induced ROS promote antigen cross-presentation of immunogenic peptides by bone marrow-derived mesenchymal stromal cells

BACKGROUND: Mesenchymal stromal cells (MSCs) have been extensively used in the clinic due to their exquisite tissue repair capacity. However, they also hold promise in the field of cellular vaccination as they can behave as conditional antigen presenting cells in response to interferon (IFN)-gamma t...

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Detalles Bibliográficos
Autores principales: Salame, Natasha, Bikorimana, Jean-Pierre, El-Hachem, Nehme, Saad, Wael, Kurdi, Mazen, Zhao, Jing, Eliopoulos, Nicoletta, Shammaa, Riam, Rafei, Moutih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751335/
https://www.ncbi.nlm.nih.gov/pubmed/35012668
http://dx.doi.org/10.1186/s13287-021-02693-z