Sialylation of IgG inhibits the formation of galactose-deficient IgA1-containing immune complexes and protects mesangial cells from injury in IgA nephropathy

BACKGROUND: The addition of sialic acid alters IgG from a pro-inflammatory state to an anti-inflammatory state. However, there is a lack of research on the changes of IgG sialylation in IgA nephropathy (IgAN). METHODS: This study included a total of 184 IgAN patients. The sialylated IgG (SA-IgG), Ig...

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Detalles Bibliográficos
Autores principales: Liu, Youxia, Li, Hongfen, Yu, Huyan, Wang, Fanghao, Jia, Junya, Yan, Tiekun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751338/
https://www.ncbi.nlm.nih.gov/pubmed/35016642
http://dx.doi.org/10.1186/s12882-021-02657-8

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