Thymosin beta-4 improves endothelial function and reparative potency of diabetic endothelial cells differentiated from patient induced pluripotent stem cells

BACKGROUND: Prior studies show that signature phenotypes of diabetic human induced pluripotent stem cells derived endothelial cells (dia-hiPSC-ECs) are disrupted glycine homeostasis, increased senescence, impaired mitochondrial function and angiogenic potential as compared with healthy hiPSC-ECs. In...

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Detalles Bibliográficos
Autores principales: Su, Liping, Kong, Xiaocen, Loo, Szejie, Gao, Yu, Liu, Bingli, Su, Xiaofei, Dalan, Rinkoo, Ma, Jianhua, Ye, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751378/
https://www.ncbi.nlm.nih.gov/pubmed/35012642
http://dx.doi.org/10.1186/s13287-021-02687-x

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