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Epigenetic mosaicism and cell burden in Beckwith–Wiedemann syndrome due to loss of methylation at imprinting control region 2

Beckwith–Wiedemann syndrome (BWS) is a rare overgrowth disorder caused by epigenetic alterations on Chromosome 11p15.5. Most molecular changes are sporadic and are thought to occur in a mosaic pattern. Thereby, the distribution of affected cells differs between tissues for each individual, which can...

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Detalles Bibliográficos
Autores principales:	Duffy, Kelly A., Hathaway, Evan R., Klein, Steven D., Ganguly, Arupa, Kalish, Jennifer M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751414/ https://www.ncbi.nlm.nih.gov/pubmed/34697083 http://dx.doi.org/10.1101/mcs.a006115

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