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Evaluation of Pediatric Hydrocephalus: Clinical, Surgical, and Outcome Perspective in a Tertiary Center

CONTEXT: Pediatric hydrocephalus (PH) results in significant clinical and psychosocial morbidity in pediatric population. AIMS: The aims of the study are to evaluate clinical, surgical, and outcome perspective of PH patients of age <12 years. SETTINGS AND DESIGN: This is a retrospective cohort st...

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Autores principales: Singh, Rahul, Prasad, Ravi Shankar, Singh, Ramit Chandra, Trivedi, Adarsh, Bhaikhel, Kulwant Singh, Sahu, Anurag
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751515/
https://www.ncbi.nlm.nih.gov/pubmed/35071066
http://dx.doi.org/10.4103/ajns.AJNS_132_21
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author Singh, Rahul
Prasad, Ravi Shankar
Singh, Ramit Chandra
Trivedi, Adarsh
Bhaikhel, Kulwant Singh
Sahu, Anurag
author_facet Singh, Rahul
Prasad, Ravi Shankar
Singh, Ramit Chandra
Trivedi, Adarsh
Bhaikhel, Kulwant Singh
Sahu, Anurag
author_sort Singh, Rahul
collection PubMed
description CONTEXT: Pediatric hydrocephalus (PH) results in significant clinical and psychosocial morbidity in pediatric population. AIMS: The aims of the study are to evaluate clinical, surgical, and outcome perspective of PH patients of age <12 years. SETTINGS AND DESIGN: This is a retrospective cohort study. MATERIALS AND METHODS: This study includes 117 pediatric patients (age ≤12 years) of hydrocephalus due to various etiology admitted in our department between September 2018 and December 2020. Demographic profile, etiology, clinical presentation, management, complications and postoperative outcome characteristics were evaluated. Survival analysis was done with respect to etiology and age group. STATISTICAL ANALYSIS USED: P < 0.05 was considered statistically significant. Unpaired t-test and Chi-square test were used. Kaplan–Meier curve plotting and survival analysis were also done. RESULTS: Male-to-female ratio was 1.3:1. Most frequent etiology of PH was postinfectious (35%). Posterior fossa pilocytic astrocytoma (34.2%) was the most common neoplastic etiology. Surgical procedure performed for PH was ventriculoperitoneal shunting (n = 103), Ommaya reservoir (n = 2) placement, and endoscopic third ventriculostomy (ETV) (n = 8). Mortality was significantly (P = 0.0139) more in patients of neoplastic etiology. Cognitive deficits and delayed developmental milestones were significantly (P < 0.05) more in congenital hydrocephalus etiology. There was a nonsignificant difference in survival between age groups (P = 0.1971). However, a significant survival difference was evident (P = 0.0098) for etiology. CONCLUSIONS: Disease-specific mortality is main cause of mortality in PH. Neoplastic etiology PH has poor survival when compared to others. Life-long routine controls are required to avoid future possible complications and enhance better rehabilitation of the child.
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spelling pubmed-87515152022-01-21 Evaluation of Pediatric Hydrocephalus: Clinical, Surgical, and Outcome Perspective in a Tertiary Center Singh, Rahul Prasad, Ravi Shankar Singh, Ramit Chandra Trivedi, Adarsh Bhaikhel, Kulwant Singh Sahu, Anurag Asian J Neurosurg Original Article CONTEXT: Pediatric hydrocephalus (PH) results in significant clinical and psychosocial morbidity in pediatric population. AIMS: The aims of the study are to evaluate clinical, surgical, and outcome perspective of PH patients of age <12 years. SETTINGS AND DESIGN: This is a retrospective cohort study. MATERIALS AND METHODS: This study includes 117 pediatric patients (age ≤12 years) of hydrocephalus due to various etiology admitted in our department between September 2018 and December 2020. Demographic profile, etiology, clinical presentation, management, complications and postoperative outcome characteristics were evaluated. Survival analysis was done with respect to etiology and age group. STATISTICAL ANALYSIS USED: P < 0.05 was considered statistically significant. Unpaired t-test and Chi-square test were used. Kaplan–Meier curve plotting and survival analysis were also done. RESULTS: Male-to-female ratio was 1.3:1. Most frequent etiology of PH was postinfectious (35%). Posterior fossa pilocytic astrocytoma (34.2%) was the most common neoplastic etiology. Surgical procedure performed for PH was ventriculoperitoneal shunting (n = 103), Ommaya reservoir (n = 2) placement, and endoscopic third ventriculostomy (ETV) (n = 8). Mortality was significantly (P = 0.0139) more in patients of neoplastic etiology. Cognitive deficits and delayed developmental milestones were significantly (P < 0.05) more in congenital hydrocephalus etiology. There was a nonsignificant difference in survival between age groups (P = 0.1971). However, a significant survival difference was evident (P = 0.0098) for etiology. CONCLUSIONS: Disease-specific mortality is main cause of mortality in PH. Neoplastic etiology PH has poor survival when compared to others. Life-long routine controls are required to avoid future possible complications and enhance better rehabilitation of the child. Wolters Kluwer - Medknow 2021-12-18 /pmc/articles/PMC8751515/ /pubmed/35071066 http://dx.doi.org/10.4103/ajns.AJNS_132_21 Text en Copyright: © 2021 Asian Journal of Neurosurgery https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Singh, Rahul
Prasad, Ravi Shankar
Singh, Ramit Chandra
Trivedi, Adarsh
Bhaikhel, Kulwant Singh
Sahu, Anurag
Evaluation of Pediatric Hydrocephalus: Clinical, Surgical, and Outcome Perspective in a Tertiary Center
title Evaluation of Pediatric Hydrocephalus: Clinical, Surgical, and Outcome Perspective in a Tertiary Center
title_full Evaluation of Pediatric Hydrocephalus: Clinical, Surgical, and Outcome Perspective in a Tertiary Center
title_fullStr Evaluation of Pediatric Hydrocephalus: Clinical, Surgical, and Outcome Perspective in a Tertiary Center
title_full_unstemmed Evaluation of Pediatric Hydrocephalus: Clinical, Surgical, and Outcome Perspective in a Tertiary Center
title_short Evaluation of Pediatric Hydrocephalus: Clinical, Surgical, and Outcome Perspective in a Tertiary Center
title_sort evaluation of pediatric hydrocephalus: clinical, surgical, and outcome perspective in a tertiary center
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751515/
https://www.ncbi.nlm.nih.gov/pubmed/35071066
http://dx.doi.org/10.4103/ajns.AJNS_132_21
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