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Parathyroid hormone signaling in mature osteoblasts/osteocytes protects mice from age-related bone loss

Aging is accompanied by osteopenia, characterized by reduced bone formation and increased bone resorption. Osteocytes, the terminally differentiated osteoblasts, are regulators of bone homeostasis, and parathyroid hormone (PTH) receptor (PPR) signaling in mature osteoblasts/osteocytes is essential f...

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Detalles Bibliográficos
Autores principales: Uda, Yuhei, Saini, Vaibhav, Petty, Christopher A., Alshehri, Majed, Shi, Chao, Spatz, Jordan M., Santos, Roberto, Newell, Carly M., Huang, Tim Y., Kochen, Alejandro, Kim, Ji W., Constantinou, Christodoulos K., Saito, Hiroaki, Held, Kathryn D., Hesse, Eric, Pajevic, Paola Divieti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751595/
https://www.ncbi.nlm.nih.gov/pubmed/34968192
http://dx.doi.org/10.18632/aging.203808