WASp triggers mechanosensitive actin patches to facilitate immune cell migration in dense tissues

When crawling through the body, leukocytes often traverse tissues that are densely packed with extracellular matrix and other cells, and this raises the question: How do leukocytes overcome compressive mechanical loads? Here, we show that the actin cortex of leukocytes is mechanoresponsive and that...

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Detalles Bibliográficos
Autores principales: Gaertner, Florian, Reis-Rodrigues, Patricia, de Vries, Ingrid, Hons, Miroslav, Aguilera, Juan, Riedl, Michael, Leithner, Alexander, Tasciyan, Saren, Kopf, Aglaja, Merrin, Jack, Zheden, Vanessa, Kaufmann, Walter Anton, Hauschild, Robert, Sixt, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751638/
https://www.ncbi.nlm.nih.gov/pubmed/34919802
http://dx.doi.org/10.1016/j.devcel.2021.11.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751638/
https://www.ncbi.nlm.nih.gov/pubmed/34919802
http://dx.doi.org/10.1016/j.devcel.2021.11.024

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