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WASp triggers mechanosensitive actin patches to facilitate immune cell migration in dense tissues
When crawling through the body, leukocytes often traverse tissues that are densely packed with extracellular matrix and other cells, and this raises the question: How do leukocytes overcome compressive mechanical loads? Here, we show that the actin cortex of leukocytes is mechanoresponsive and that...
Autores principales: | Gaertner, Florian, Reis-Rodrigues, Patricia, de Vries, Ingrid, Hons, Miroslav, Aguilera, Juan, Riedl, Michael, Leithner, Alexander, Tasciyan, Saren, Kopf, Aglaja, Merrin, Jack, Zheden, Vanessa, Kaufmann, Walter Anton, Hauschild, Robert, Sixt, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751638/ https://www.ncbi.nlm.nih.gov/pubmed/34919802 http://dx.doi.org/10.1016/j.devcel.2021.11.024 |
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