Cargando…

Synthesis and Antiviral Activities of Neoechinulin B and Its Derivatives

[Image: see text] We have previously reported that neoechinulin B (1a), a prenylated indole diketopiperazine alkaloid, shows antiviral activities against hepatitis C virus (HCV) via the inactivation of the liver X receptors (LXRs) and the resultant disruption of double-membrane vesicles. In this stu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nishiuchi, Kota, Ohashi, Hirofumi, Nishioka, Kazane, Yamasaki, Masako, Furuta, Masateru, Mashiko, Takumi, Tomoshige, Shusuke, Ohgane, Kenji, Kamisuki, Shinji, Watashi, Koichi, Kuramochi, Kouji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society and American Society of Pharmacognosy 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751641/ https://www.ncbi.nlm.nih.gov/pubmed/34967639 http://dx.doi.org/10.1021/acs.jnatprod.1c01120

Ejemplares similares

Synthesis and Cytotoxic Evaluation of N-Alkyl-2-halophenazin-1-ones
por: Kohatsu, Haruki, et al.
Publicado: (2020)

Synthesis and Neuroprotective Action of Optically Pure Neoechinulin A and Its Analogs
por: Aoki, Toshiaki, et al.
Publicado: (2010)

Isolation, structural determination, and antiviral activities of metabolites from vanitaracin A-producing Talaromyces sp.
por: Kamisuki, Shinji, et al.
Publicado: (2022)

Should a viral genome stay in the host cell or leave? A quantitative dynamics study of how hepatitis C virus deals with this dilemma
por: Iwanami, Shoya, et al.
Publicado: (2020)

Therapeutic Potential of Neoechinulins and Their Derivatives: An Overview of the Molecular Mechanisms Behind Pharmacological Activities
por: Sharifi-Rad, Javad, et al.
Publicado: (2021)

Identification of Anti-Severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV-2) Oxysterol Derivatives In Vitro
por: Ohashi, Hirofumi, et al.
Publicado: (2021)

Mefloquine, a Potent Anti-severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV-2) Drug as an Entry Inhibitor in vitro
por: Shionoya, Kaho, et al.
Publicado: (2021)

Antiviral Activity of Micafungin and Its Derivatives against SARS-CoV-2 RNA Replication
por: Nakajima, Shogo, et al.
Publicado: (2023)

Unified Approach toward Syntheses of Juglomycins and Their Derivatives
por: Yoshioka, Kai, et al.
Publicado: (2019)

Fungal Secondary Metabolite Exophillic Acid Selectively Inhibits the Entry of Hepatitis B and D Viruses
por: Kobayashi, Chisa, et al.
Publicado: (2022)

Potential anti-COVID-19 agents, cepharanthine and nelfinavir, and their usage for combination treatment
por: Ohashi, Hirofumi, et al.
Publicado: (2021)

Identifying and repurposing antiviral drugs against severe acute respiratory syndrome coronavirus 2 with in silico and in vitro approaches
por: Watashi, Koichi
Publicado: (2021)

Correction to: Required concentration index quantifies effective drug combinations against hepatitis C virus infection
por: Kakizoe, Yusuke, et al.
Publicado: (2021)

Required concentration index quantifies effective drug combinations against hepatitis C virus infection
por: Kakizoe, Yusuke, et al.
Publicado: (2021)

Neoechinulin A as a Promising SARS-CoV-2 M(pro) Inhibitor: In Vitro and In Silico Study Showing the Ability of Simulations in Discerning Active from Inactive Enzyme Inhibitors
por: Alhadrami, Hani A., et al.
Publicado: (2022)

Different efficacies of neutralizing antibodies and antiviral drugs on SARS-CoV-2 Omicron subvariants, BA.1 and BA.2
por: Ohashi, Hirofumi, et al.
Publicado: (2022)

Development of novel monoclonal antibodies against nsp12 of SARS-CoV-2
por: Machitani, Mitsuhiro, et al.
Publicado: (2022)

TRPA1-dependent reversible opening of tight junction by natural compounds with an α,β-unsaturated moiety and capsaicin
por: Kanda, Yusuke, et al.
Publicado: (2018)

Cyclosporin A Associated Helicase-Like Protein Facilitates the Association of Hepatitis C Virus RNA Polymerase with Its Cellular Cyclophilin B
por: Morohashi, Kengo, et al.
Publicado: (2011)

Anti-Inflammatory Effect of Neoechinulin A from the Marine Fungus Eurotium sp. SF-5989 through the Suppression of NF-кB and p38 MAPK Pathways in Lipopolysaccharide-Stimulated RAW264.7 Macrophages
por: Kim, Kyoung-Su, et al.
Publicado: (2013)

Dasabuvir Inhibits Human Norovirus Infection in Human Intestinal Enteroids
por: Hayashi, Tsuyoshi, et al.
Publicado: (2021)

Epigenetic reprogramming promotes the antiviral action of IFNα in HBV-infected cells
por: Gailhouste, Luc, et al.
Publicado: (2021)

Selective Degradation of Target Proteins by Chimeric Small-Molecular Drugs, PROTACs and SNIPERs
por: Ishikawa, Minoru, et al.
Publicado: (2020)

Antiviral activity of ciclesonide acetal derivatives blocking SARS-CoV-2 RNA replication
por: Tsuji, Genichiro, et al.
Publicado: (2022)

Molecular dissection of HBV evasion from restriction factor tetherin: A new perspective for antiviral cell therapy
por: Miyakawa, Kei, et al.
Publicado: (2015)

A quantitative model used to compare within-host SARS-CoV-2, MERS-CoV, and SARS-CoV dynamics provides insights into the pathogenesis and treatment of SARS-CoV-2
por: Kim, Kwang Su, et al.
Publicado: (2021)

Engineering Cellular Biosensors with Customizable Antiviral Responses Targeting Hepatitis B Virus
por: Matsunaga, Satoko, et al.
Publicado: (2020)

Penetration through Outer Membrane and Efflux Potential in Pseudomonas aeruginosa of Bulgecin A as an Adjuvant to β-Lactam Antibiotics
por: Kim, Choon, et al.
Publicado: (2023)

Antiviral Activity of Glycyrrhizin against Hepatitis C Virus In Vitro
por: Matsumoto, Yoshihiro, et al.
Publicado: (2013)

Rapidly Enlarging Pediatric Cortical Ependymoma
por: Yamasaki, Kouji, et al.
Publicado: (2015)

Semiflow Microwave Heating Reactor with Resonator Moving Mechanism Applied to Zeolite Synthesis
por: Nishioka, Masateru, et al.
Publicado: (2022)

Human Monoclonal Antibodies against Cytokeratin 18 Generated from Patients with Gastric Cancer
por: Abe, Tsutomu, et al.
Publicado: (1989)

Hypochlorous acid solution is a potent antiviral agent against SARS‐CoV‐2
por: Hatanaka, Noritoshi, et al.
Publicado: (2021)

Cyclophilin and Viruses: Cyclophilin as a Cofactor for Viral Infection and Possible Anti-Viral Target
por: Watashi, Koichi, et al.
Publicado: (2007)

Functionalization of Human Serum Albumin by Tyrosine Click
por: Obara, Satsuki, et al.
Publicado: (2021)

Cross-breed comparisons identified a critical 591-kb region for bovine carcass weight QTL (CW-2) on chromosome 6 and the Ile-442-Met substitution in NCAPG as a positional candidate
por: Setoguchi, Kouji, et al.
Publicado: (2009)

Thoracoscopic surgery for lung emphysema using an infrared camera
por: Matsumoto, Keitaro, et al.
Publicado: (2013)

Estimation of the incubation period of COVID-19 using viral load data
por: Ejima, Keisuke, et al.
Publicado: (2021)

The defense response in Arabidopsis thaliana against Fusarium sporotrichioides
por: Asano, Tomoya, et al.
Publicado: (2012)

Proteomic Profiling of Plant and Pathogen Interaction on the Leaf Epidermis
por: Sidiq, Yasir, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_608vha6f9q3bel4iu10p1ffvt6