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Unravelling Atrioventricular Block Risk in Inflammatory Diseases: Systemic Inflammation Acutely Delays Atrioventricular Conduction via a Cytokine‐Mediated Inhibition of Connexin43 Expression

BACKGROUND: Recent data suggest that systemic inflammation can negatively affect atrioventricular conduction, regardless of acute cardiac injury. Indeed, gap‐junctions containing connexin43 coupling cardiomyocytes and inflammation‐related cells (macrophages) are increasingly recognized as important...

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Detalles Bibliográficos
Autores principales: Lazzerini, Pietro Enea, Acampa, Maurizio, Cupelli, Michael, Gamberucci, Alessandra, Srivastava, Ujala, Nanni, Claudio, Bertolozzi, Iacopo, Vanni, Francesca, Frosali, Alessandro, Cantore, Anna, Cartocci, Alessandra, D’Errico, Antonio, Salvini, Viola, Accioli, Riccardo, Verrengia, Decoroso, Salvadori, Fabio, Dokollari, Aleksander, Maccherini, Massimo, El‐Sherif, Nabil, Laghi‐Pasini, Franco, Capecchi, Pier Leopoldo, Boutjdir, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751850/
https://www.ncbi.nlm.nih.gov/pubmed/34713715
http://dx.doi.org/10.1161/JAHA.121.022095