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Bilirubin Nanoparticles Protect Against Cardiac Ischemia/Reperfusion Injury in Mice
BACKGROUND: Ischemia/reperfusion (I/R) injury causes overproduction of reactive oxygen species, which are the major culprits of oxidative stress that leads to inflammation, apoptosis, myocardial damage, and dysfunction. Bilirubin acts as a potent endogenous antioxidant that is capable of scavenging...
Autores principales: | Ai, Wen, Bae, Soochan, Ke, Qingen, Su, Shi, Li, Ruijian, Chen, Yanwei, Yoo, Dohyun, Lee, Eesac, Jon, Sangyong, Kang, Peter M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751875/ https://www.ncbi.nlm.nih.gov/pubmed/34622671 http://dx.doi.org/10.1161/JAHA.121.021212 |
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